Sysmex XS500/XS800/XS1000

Description

The XS-series is a great addition to Sysmex’s X-Class hematology analyzers. Despite being the smallest, its quality is undiminished. Its fluorescence flow cytometry technology delivers extremely high quality all around. With a complete differential blood count for all white blood cell populations, and an excellent determination of red blood cells and platelets enhanced by hydrodynamic focusing. Hemoglobin measurements are equally impressive since the XS-series retains a dedicated hemoglobin channel.

One of the key distinctions of the XS-series is the aspiration volume of just 20 micro liters, which will benefit those with neonatal and pediatric samples.

We have taken onboard lessons learned with the other X-Class analyzers to make your life in the laboratory easier. User maintenance has been reduced further – with minimal automatic shutdown time, and there’s a new type of Sample Explorer to simplify sample management.

All XS-series analyzers are specifically crafted for laboratories that, despite smaller throughputs, still need to deliver detailed, reliable and highly accurate results.

Fluorescence flow cytometry can really help you

Fluorescence flow cytometry is used to analyze physiological and chemical properties of cells. It can also be used to analyze other biological particles in urinalysis analysers. It provides:

• Information about cell size and structure
• Information about a cell’s interior

In flow cytometry, we examine cells and particles while they are flowing through a very narrow flow cell.

First a blood sample is aspirated and proportioned, then diluted to a pre-set ratio and labeled with a proprietary fluorescence marker that binds specifically to nucleic acids.

Next the sample is transported into the flow cell. The sample is illuminated by a semiconductor laser beam, which can separate the cells using three different signals:

• forward scattered light (forward scatter or FSC)
• side scattered light (side scatter or SSC)
• side fluorescence light (side fluorescence or SFL).

The intensity of the forward scatter indicates the cell volume. The side scatter provides information about the cell content, such as nucleus and granules. The side fluorescence indicates the amount of DNA and RNA present in the cell.

Cells with similar physical and chemical properties form a cluster in a graph known as a scattergram.

The principle of fluorescence flow cytometry is used in different analyzers for hematology and urinalysis. For blood cell counts we use fluorescence flow cytometry, e.g. for the WBC and differential, for NRBC counting and reticulocyte measurement.

In urinalysis analyzers, fluorescence technology is also used for counting bacteria, red blood cells, white blood cells and other elements.

 

Sysmex XS-500

technologies	fluorescence flow cytometry: WBC DIFF, IG DC sheath flow method: RBC, HCT, PLT cyanide-free SLS method: HGB
Diagnostic parameters	WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT, RDW-SD, RDW-CV, PDW, MPV, P-LCR, PCT, NEUT%, LYMPH%, MONO%, EO%, BASO%, NEUT#, LYMPH#, MONO#, EO#, BASO#
Research parameters	IG%, IG#, Other%, Other#
Throughput	up to 60 samples/hour
Aspiration volume	approx. 20 microL (manual open/closed mode, capillary mode, sampler mode)
Data storage	up to 8,000 samples (incl. graphics); up to 5,000 patients’ information; 20 quality control files in simpler mode)
Quality control	Xbar, Levey-Jennings, XbarM
Dimensions/weight	WxHxD [mm]/[kg] 320×503 x413 /approx. 24

 

 

Sysmex XS-800

Technologies	fluorescence flow cytometry: WBC DIFF, IG DC sheath flow method: RBC, HCT, PLT cyanide-free SLS method: HGB
Diagnostic parameters	WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT, RDW-SD, RDW-CV, PDW, MPV, P-LCR, PCT, NEUT%, LYMPH%, MONO%, EO%, BASO%, NEUT#, LYMPH#, MONO#, EO#, BASO#
Research parameters	IG%, IG#, Other%, Other#
Throughput	up to 60 samples/hour
Aspiration volume	approx. 20 microL (manual open/closed mode, capillary mode, sampler mode)
Data storage	up to 10,000 samples (incl. graphics); up to 5,000 patients’ information; 20 quality control files
Quality control	Xbar, Levey-Jennings, XbarM
Dimensions/weights	WxHxD [mm]/[kg] 320×503 x413 /approx. 24 (XS-800i main unit)

 

Sysmex XS-1000

Technologies	fluorescence flow cytometry: WBC DIFF DC sheath flow method: RBC, HCT, PLT cyanide-free SLS method: HGB
Diagnostic parameters	WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT, RDW-SD, RDW-CV, PDW, MPV, P-LCR, PCT, NEUT%, LYMPH%, MONO%, EO%, BASO%, NEUT#, LYMPH#, MONO#, EO#, BASO#
Research parameters	IG%, IG#, Other%, Other#
Throughput	up to 60 samples/hour
Aspiration volume	approx. 20 microL (manual open/closed mode, sampler mode)
Data storage	up to 10,000 samples (incl. graphics); up to 5,000 patients’ information; 20 quality control files ode)
Quality control	Xbar, Levey-Jennings, XbarM
Dimensions/weights	WxHxD [mm]/[kg] 320×403 x413 /approx. 24 (XS-1000i main unit) 450x420x630/approx. 38 (XS-1000i with optional sampler)